CBDA Research
Obesity and CBDA in Mice
antioxidant Effects + CBDA with CBD
CBDA effects on SARS-CoV-2
CBDA ameliorated obesity in associated with metabolic abnormalities in mice.
CBDA effects on SARS-CoV-2
antioxidant Effects + CBDA with CBD
CBDA effects on SARS-CoV-2
Cannabinoid acids from hemp were found to be allosteric as well as orthosteric ligands with micromolar affinity for the spike protein reducing entry of SARS-CoV-2 into the body.
antioxidant Effects + CBDA with CBD
antioxidant Effects + CBDA with CBD
antioxidant Effects + CBDA with CBD
Metabolomic Profile and Antioxidant/Anti-Inflammatory Effects of Industrial Hemp Water Extract in Fibroblasts, Keratinocytes and Isolated Mouse Skin Specimens
BCRP: drug efflux transporter
BCRP: drug efflux transporter
antioxidant Effects + CBDA with CBD
Cannabis constituents interact at the drug efflux pump BCRP to markedly increase plasma cannabidiolic acid concentrations
MB-231: Breast Cancer
BCRP: drug efflux transporter
MB-231: Breast Cancer
Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration
5-HT1A: nausea
BCRP: drug efflux transporter
MB-231: Breast Cancer
Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT1A receptor activation
Cancer, COx2, PPAR
Cancer, COx2, PPAR
Cancer, COx2, PPAR
Cannabidiolic acid dampens the expression of cyclooxygenase-2 in MDA-MB-231 breast cancer cells: Possible implication of the peroxisome proliferator-activated receptor β/δ abrogation
COX2: Inflammation
Cancer, COx2, PPAR
Cancer, COx2, PPAR
Cannabidiolic acid as a selective cyclooxygenase-2 inhibitory component in cannabis
dual PPAR agonists
Cancer, COx2, PPAR
dual PPAR agonists
Identification and characterization of phytocannabinoids as novel dual PPARα/γ agonists by a computational and in vitro experimental approach
TRP channels
Rett syndrome
dual PPAR agonists
Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on
TRP channels and endocannabinoid metabolic enzymes
Rett syndrome
Rett syndrome
Rett syndrome
Chronic treatment with cannabidiolic acid (CBDA) reduces thermal pain sensitivity in male mice and rescues the hyperalgesia in a mouse model of Rett syndrome
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